Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 14/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715998 | 0.97 | S1PR3 (0.42) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL23715847 | 0.88 | S1PR3 (0.42) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL23716138 | 0.80 | LMNA (0.34) | S1PR3S1PR4SLC6A4CNR2 | |
| SCHEMBL23715872 | 0.75 | S1PR3 (0.40) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL23715832 | 0.73 | S1PR3 (0.58) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL23715829 | 0.72 | S1PR3 (0.44) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17663930 | 0.72 | S1PR3 (0.47) | S1PR3S1PR1S1PR4S1PR2CNR2 | |
| SCHEMBL23716117 | 0.72 | OGG1 (0.38) | SLC6A4CNR1CNR2 | |
| SCHEMBL23715916 | 0.69 | OGG1 (0.44) | SLC6A4 | |
| SCHEMBL23715936 | 0.68 | NPC1 (0.44) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |