Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584703 | 0.80 | NPC1 (0.53) | MEN1KMT2AFPR2RAB9ANPC1 | |
| SCHEMBL23715809 | 0.77 | NPC1 (0.50) | MEN1KMT2AFPR2RAB9ANPC1 | |
| SCHEMBL17664140 | 0.76 | RAB9A (0.56) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL17663794 | 0.75 | NPC1 (0.51) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL17663823 | 0.73 | MEN1 (0.55) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL17663889 | 0.73 | S1PR3 (0.59) | — | |
| SCHEMBL17663821 | 0.72 | RAB9A (0.64) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL17664138 | 0.71 | ALDH1A1 (0.56) | RAB9ANPC1MMP8MMP14CA14 | |
| SCHEMBL21391854 | 0.71 | PYGL (0.52) | MEN1KMT2AFPR2PLAAT3PLAAT5 | |
| SCHEMBL18228901 | 0.71 | PYGL (0.52) | MEN1KMT2AFPR2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |