Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716215 | 0.89 | MBOAT4 (0.37) | RXRAGRIN1GRIN2BMBOAT4DAO | |
| SCHEMBL17664100 | 0.85 | FYN (0.41) | MPOMBOAT4DAOHSP90AB1 | |
| SCHEMBL17664358 | 0.84 | HDAC3 (0.41) | DAOSLC6A4KCNH2HTR2AHSP90AB1 | |
| SCHEMBL17664001 | 0.83 | GPR52 (0.35) | MBOAT4DAOSLC6A4KCNH2HTR2A | |
| SCHEMBL23716203 | 0.83 | MBOAT4 (0.39) | MBOAT4MCHR1SLC6A4KCNH2HTR2A | |
| SCHEMBL17663975 | 0.78 | RAB9A (0.48) | MBOAT4HSP90AB1RAB9A | |
| SCHEMBL17663971 | 0.77 | HSP90AB1 (0.47) | MBOAT4SLC6A2SLC6A3HSP90AB1 | |
| SCHEMBL17663857 | 0.77 | IDO1 (0.42) | SLC6A4SLC6A2SLC6A3HSP90AB1 | |
| SCHEMBL17664105 | 0.76 | MEN1 (0.40) | MBOAT4RAB9A | |
| SCHEMBL17971122 | 0.75 | ESR1 (0.54) | MMP13MPODAOSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |