Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601105 | 0.85 | TRPA1 (0.39) | TRPA1L3MBTL1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL30707413 | 0.85 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6LMNAMAPK1 | |
| SCHEMBL321279 | 0.85 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6LMNAMAPK1 | |
| SCHEMBL31460200 | 0.85 | CYP4F2 (0.44) | TRPA1L3MBTL1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL20059251 | 0.85 | TRPA1 (0.39) | TRPA1CYP1A2CYP2A6NPC1MAPT | |
| SCHEMBL16258888 | 0.85 | TRPA1 (0.39) | TRPA1L3MBTL1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL13179975 | 0.85 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL3759408 | 0.85 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL5847395 | 0.85 | CSNK2A1 (0.57) | L3MBTL1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5847393 | 0.85 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1706811-A | Prepn process of 4,4'-methylene-bis(3-chloro-2,6-diethyl aniline) (MCDEA) | LU JINXIAN (CN) | 2005-12-14 | — | — | CN | claimed |
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2023-05-04 | — | — | US | disclosed |
| WO-2021158464-A1 | REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-2240452-B1 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES AS PI3 KINASE MODULATORS, THEIR COMPOSITIONS AND USES | INTELLIKINE LLC (US) | 2019-05-29 | — | — | EP | disclosed |
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | disclosed |
| EP-2440572-B1 | LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| CN-101328144-B | Method for synthesizing indoline and derivates thereof | NINGBO INST TECH ZHEJIANG UNIV | 2011-01-19 | — | — | CN | disclosed |
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| CN-101328144-A | Method for synthesizing indoline and derivates thereof | NINGBO INST TECH ZHEJIANG UNIV (CN) | 2008-12-24 | — | — | CN | disclosed |
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-1081122-B1 | Method for isomerizing halogenated ethylbenzene | TORAY INDUSTRIES (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-6235952-B1 | ISOMERIZATION OF HALOGENATED ETHYLBENZENE USING ACIDIC ZEOLITE WITH METAL FROM GROUP 7 TO 11 | TORAY INDUSTRIES, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-1081122-A1 | Method for isomerizing halogenated ethylbenzene | TORAY INDUSTRIES, INC. (JP) | 2001-03-07 | — | — | EP | disclosed |
| EP-0894782-A1 | METHOD FOR ISOMERIZING HALOGENATED ETHYLBENZENE AND METHOD FOR SEPARATING HALOGENATED ETHYLBENZENE ISOMERS | TORAY INDUSTRIES, INC. (JP) | 1999-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | IDUA, MAN2B1, GBA1 | TRPA1 4690/4885L3MBTL1 138/4885CYP1A2 1487/4885 |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TRPA1 762/4885L3MBTL1 3838/4885CYP1A2 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.