SCHEMBL23717895

SCHEMBL23717895

C=C(Nc1cc(C(C)C)ccc1C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MYOC Q99972 1/20 0.50
TRPA1 O75762 1/20 0.47
PTGS1 P23219 1/20 0.47
CACNA1C Q13936 1/20 0.47
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 3/20 0.37
BCHE P06276 1/20 0.37
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18930369 0.86 TRPA1 (0.43) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL20707093 0.84 MEN1 (0.51) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL26080097 0.82 ALDH1A1 (0.47) MEN1KMT2AMAPTNPSR1ALDH1A1
SCHEMBL18932088 0.80 MEN1 (0.47) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL21568091 0.79 MEN1 (0.58) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL13170071 0.77 MEN1 (0.57) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL20825702 0.76 MEN1 (0.56) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL8295751 0.76 MEN1 (0.51) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL25490648 0.76 MEN1 (0.52) MEN1KMT2AMAPTNPSR1MYOC
SCHEMBL11636315 0.75 LMNA (0.56) MEN1KMT2AMAPTNPSR1MYOC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ATXN2L, ATXN2, ATXN10 MEN1 3416/4885KMT2A 2202/4885MAPT 446/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS MEN1 4681/4885KMT2A 4093/4885MAPT 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.