Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 4/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203287 | 0.79 | BCAT2 (0.39) | BCAT2LMNAHPGDSYKTRPA1 | |
| SCHEMBL20203286 | 0.76 | TRPA1 (0.45) | BCAT2LMNAHPGDSYKTRPA1 | |
| SCHEMBL20203370 | 0.73 | TRPA1 (0.46) | BCAT2LMNAHPGDSYKTRPA1 | |
| SCHEMBL20203176 | 0.69 | TRPA1 (0.41) | BCAT2LMNAHPGDSYKTRPA1 | |
| SCHEMBL20203179 | 0.65 | TRPA1 (0.42) | BCAT2LMNAHPGDSYKTRPA1 | |
| SCHEMBL18964872 | 0.62 | MAPT (0.43) | BCAT2LMNAHPGDMAPTTHRB | |
| SCHEMBL15801414 | 0.62 | PARP1 (0.49) | BCAT2LMNAHPGDTRPA1 | |
| SCHEMBL24242354 | 0.62 | ALDH1A1 (0.34) | BCAT2LMNAHPGDSYKF2RL3 | |
| SCHEMBL15801422 | 0.62 | F2RL3 (0.40) | BCAT2LMNAHPGDF2RL3 | |
| SCHEMBL23718230 | 0.61 | ADORA2B (0.33) | BCAT2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544979-B1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-08-04 | — | — | EP | disclosed |