Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 2/20 | 0.45 |
| ▸ | ATP4B | P51164 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071164 | 0.81 | PTPN1 (0.42) | ABL1ALDH1A1KDM4EPTPN1ATP4A | |
| SCHEMBL30526610 | 0.78 | CYP1A1 (0.43) | ABL1ADORA1CYP3A4ADORA2AAPP | |
| SCHEMBL23720038 | 0.77 | CYP3A4 (0.43) | ALDH1A1KDM4EATP4AATP4BSMN1; SMN2 | |
| SCHEMBL25909688 | 0.74 | PIK3CA (0.34) | ABL1ALDH1A1KDM4EADORA1SMN1; SMN2 | |
| SCHEMBL24071100 | 0.74 | MPL (0.45) | ALDH1A1PTPN1HPGDMEN1NPC1 | |
| SCHEMBL31347459 | 0.73 | PI4KA (0.60) | ABL1ADORA1CYP3A4 | |
| SCHEMBL234658 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSP90AA1HSP90AB1ATP4A | |
| SCHEMBL29796690 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSP90AA1HSP90AB1ATP4A | |
| SCHEMBL184747 | 0.72 | PIK3CD (0.50) | ALDH1A1SMN1; SMN2CYP3A4TDP1NPC1 | |
| SCHEMBL30189832 | 0.72 | PIK3CD (0.50) | ALDH1A1SMN1; SMN2CYP3A4TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | SAIL BIOMEDICINES, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | SAIL BIOMEDICINES, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | AHR, ARNT, AIPL1 | ABL1 950/4885ALDH1A1 799/4885KDM4E 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.