Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720208 | 0.84 | HTR7 (0.47) | HTR7 | |
| SCHEMBL23720203 | 0.84 | HTR7 (0.47) | HTR7 | |
| SCHEMBL23720156 | 0.75 | GAA (0.38) | HTR7 | |
| SCHEMBL23720100 | 0.66 | GAA (0.36) | HTR7HTR1AHTR2A | |
| SCHEMBL23720025 | 0.66 | GAA (0.36) | HTR7HTR1AHTR2A | |
| SCHEMBL23720027 | 0.63 | TDP1 (0.36) | HTR7 | |
| SCHEMBL23720151 | 0.63 | TDP1 (0.36) | HTR7 | |
| SCHEMBL23720153 | 0.63 | TDP1 (0.36) | HTR7 | |
| SCHEMBL23720202 | 0.61 | HSD11B1 (0.32) | HTR7 | |
| SCHEMBL23720238 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | HTR7 3034/4885CNR1 375/4885SLC2A1 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.