SCHEMBL2372252

SCHEMBL2372252

O=S(=O)(N[C]1CC1)c1ccc(Cl)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ITGA1 P56199 4/20 0.55
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
ALOX12 P18054 1/20 0.52
KMT2A Q03164 1/20 0.52
NLRP1 Q9C000 1/20 0.52
MCL1 Q07820 3/20 0.51
HPGD P15428 1/20 0.51
TSHR P16473 1/20 0.51
EDNRA P25101 2/20 0.51
SLC40A1 Q9NP59 3/20 0.49
EDNRB P24530 1/20 0.49
HDAC1 Q13547 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
PPARG P37231 3/20 0.47
CYP3A4 P08684 1/20 0.46
CCR4 P51679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588364 0.79 SLC40A1 (0.63) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL7577795 0.77 ITGA1 (0.74) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL418863 0.77 MAPT (0.50) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL3268657 0.76 MAPT (0.61) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL2029062 0.76 ITGA1 (0.68) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL2371049 0.76 MEN1 (0.49) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL2371055 0.76 CA12 (0.53) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL94831 0.75 MAPT (0.63) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL14018772 0.75 MAPT (0.63) ITGA1MEN1LMNAMAPTALOX12
SCHEMBL7577319 0.75 SLC40A1 (0.63) ITGA1MEN1LMNAMAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST ITGA1 4812/4885MEN1 4795/4885LMNA 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.