Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029062 | 0.88 | ITGA1 (0.68) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL31696798 | 0.86 | MAPK1 (0.70) | ITGA1MAPTMEN1LMNAKMT2A | |
| SCHEMBL13631960 | 0.85 | ITGA1 (1.00) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL3268657 | 0.85 | MAPT (0.61) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL7588364 | 0.84 | SLC40A1 (0.63) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL14018772 | 0.83 | MAPT (0.63) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL3763976 | 0.83 | PGR (0.55) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL28121241 | 0.83 | MAPT (0.63) | ITGA1MAPTMEN1LMNAALOX12 | |
| SCHEMBL3771893 | 0.83 | CCR2 (0.60) | ITGA1CNR2PGRGPR27SLC40A1 | |
| SCHEMBL94831 | 0.83 | MAPT (0.63) | ITGA1MAPTMEN1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |