Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.63 |
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ITGA1 | P56199 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588364 | 0.88 | SLC40A1 (0.63) | SLC40A1PPARGMCL1HPGDTSHR | |
| SCHEMBL7571597 | 0.85 | SLC40A1 (0.64) | SLC40A1PPARGMCL1HPGDTSHR | |
| SCHEMBL4799558 | 0.81 | SLC40A1 (0.56) | SLC40A1PPARGMCL1HPGDTSHR | |
| SCHEMBL4799566 | 0.81 | ALDH1A1 (0.63) | SLC40A1MCL1HPGDTSHRITGA1 | |
| SCHEMBL7577795 | 0.80 | ITGA1 (0.74) | SLC40A1PPARGITGA1MEN1LMNA | |
| SCHEMBL9930865 | 0.79 | CCR2 (0.76) | — | |
| SCHEMBL23141245 | 0.78 | ACLY (0.60) | SLC40A1HPGDITGA1MEN1LMNA | |
| SCHEMBL31261221 | 0.78 | ACLY (0.60) | SLC40A1HPGDITGA1MEN1LMNA | |
| SCHEMBL11973322 | 0.78 | SLC40A1 (1.00) | SLC40A1MEN1KMT2A | |
| SCHEMBL30925515 | 0.78 | SLC40A1 (1.00) | SLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |