SCHEMBL469832

SCHEMBL469832

CNCCCN(C)CCN(C)CCCNC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.48
CARM1 Q86X55 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
PRMT1 Q99873 1/20 0.48
PRMT8 Q9NR22 1/20 0.48
CA12 O43570 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
EPHX1 P07099 1/20 0.39
CHRM2 P08172 1/20 0.38
S1PR2 O95136 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231390 0.97 PRMT3 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL26929242 0.94 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16317337 0.94 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL10045279 0.94 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL15775227 0.94 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12571523 0.92 CA12 (0.55) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL19546063 0.92 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL11441189 0.92 PRMT1 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14579610 0.90 PRMT3 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14178222 0.89 EPHX1 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20150322252-A1 FLAME RETARDANT POLYMER COMPOSITIONS POLYAD SERVICES LLC (US) 2015-11-12 US disclosed
US-8846788-B2 Polyacetal resin composition, resin molded article, and method and agent for improving polyacetal resin raw material composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2014-09-30 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-8518302-B2 Stabilization of organic materials BASF SE (DE) 2013-08-27 US disclosed
US-8399536-B2 Irradiated polyolefin composition comprising a non-phenolic stabilizer Basell Poliolefine Italia, s.r.l. (IT) 2013-03-19 US disclosed
US-8357324-B2 Rotomolding process for polyethylene articles BASF SE (DE) 2013-01-22 US disclosed
US-8304477-B2 Liquid oxyalkylene bridged bis- and Tris-phosphite ester mixtures BASF SE (DE) 2012-11-06 US disclosed
US-20120225980-A1 METHODS OF FLAME RETARDING POLYETHYLENE PROCESSED AT HIGH TEMPERATURES BASF SE (DE) 2012-09-06 US disclosed
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS GERSTER MICHELE (CH) 2012-04-12 US disclosed
US-20100113637-A1 IRRADIATED POLYOLEFIN COMPOSITION COMPRISING A NON-PHENOLIC STABILIZER BASELL POLIOLEFINE ITALIA S.R.L, (IT) 2010-05-06 US disclosed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
US-20090093572-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-09 US disclosed
US-7514526-B2 Process for preparing a stabilized polyester CIBA SPECIALTY CHEMICALS CORP. (US) 2009-04-07 US disclosed
US-20080194743-A1 processing stabilizer selected from the group consisting of hydroxylamine stabilizers, and an antistatic agent selected from an ethoxylated amine and/or an ethoxylated amide, as stabilizers for protecting organic materials ROTZINGER BRUNO 2008-08-14 US disclosed
US-7375149-B2 Stabilization of organic materials CIBA SPECIALTY CHEMICALS CORP. (US) 2008-05-20 US disclosed
US-7332105-B2 Synergistic UV absorber combination CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-19 US disclosed
US-20070257234-A1 Stabilization of Organic Materials CIBA CORPORATION 2007-11-08 US disclosed
US-20070197697-A1 Stabilized polyolefin compositions BOTKIN JAMES H 2007-08-23 US disclosed
US-7205379-B2 reacting diacids or diesters with a diol in the presence of a stabilizer of a polyhydric alcohol, a phosphinic acid, a sterically hindered amine or a polyacrylamide; packaging with low aldehyde generation CIBA SPECIALTY CHEMICALS CORP. (US) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS LPO, AOX1, SOD1 PRMT3 3420/4885CARM1 1815/4885PRMT6 3061/4885
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M PRMT3 969/4885CARM1 495/4885PRMT6 1113/4885
US-20070257234-A1 Stabilization of Organic Materials LPO, SOD1, GPX1 PRMT3 3522/4885CARM1 2036/4885PRMT6 3031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.