Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699763 | 0.92 | HSD11B1 (0.50) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23733156 | 0.83 | TSHR (0.43) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23733149 | 0.80 | ELANE (0.44) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23733161 | 0.80 | HSD11B1 (0.59) | HSD11B1ALDH1A1L3MBTL1TSHRKMT2A | |
| SCHEMBL21897070 | 0.79 | NR3C2 (0.40) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL1021022 | 0.79 | HSD11B1 (0.45) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8178064 | 0.77 | HSD11B1 (0.44) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL27499593 | 0.76 | HSD11B1 (0.42) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23733160 | 0.76 | HSD11B1 (0.45) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11832256 | 0.76 | HSD11B1 (0.52) | HSD11B1NR3C2ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | HSD11B1 602/4885NR3C2 1104/4885ALDH1A1 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.