Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733156 | 0.84 | TSHR (0.43) | SMN1; SMN2MAPTHSD11B1ALDH1A1KMT2A | |
| SCHEMBL23733150 | 0.84 | HSD11B1 (0.50) | ELANESMN1; SMN2MAPTHSD11B1ALDH1A1 | |
| SCHEMBL23699763 | 0.84 | HSD11B1 (0.50) | SMN1; SMN2HSD11B1ALDH1A1KMT2ANR3C2 | |
| SCHEMBL23733159 | 0.80 | HSD11B1 (0.47) | SMN1; SMN2HSD11B1ALDH1A1KMT2ANR3C2 | |
| SCHEMBL21897070 | 0.72 | NR3C2 (0.40) | SMN1; SMN2MAPTHSD11B1ALDH1A1KMT2A | |
| SCHEMBL1021022 | 0.71 | HSD11B1 (0.45) | SMN1; SMN2MAPTHSD11B1ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL8178064 | 0.70 | HSD11B1 (0.44) | SMN1; SMN2MAPTHSD11B1ALDH1A1PKM | |
| SCHEMBL23733152 | 0.70 | HSD11B1 (0.55) | MAPTHSD11B1ALDH1A1PKMKMT2A | |
| SCHEMBL23733160 | 0.69 | HSD11B1 (0.45) | SMN1; SMN2MAPTHSD11B1ALDH1A1KMT2A | |
| SCHEMBL27499593 | 0.69 | HSD11B1 (0.42) | MAPTHSD11B1ALDH1A1KMT2ANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | ELANE 932/4885SMN1; SMN2 262/4885MAPT 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.