SCHEMBL23733880

SCHEMBL23733880

Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc(-c5cccnc5)cc(-c5cccnc5)c4)cc3)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP2A6 P11509 2/20 0.50
CYP11B1 P15538 4/20 0.49
MKNK1 Q9BUB5 3/20 0.49
MKNK2 Q9HBH9 3/20 0.49
CYP11B2 P19099 3/20 0.49
CYP17A1 P05093 2/20 0.49
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ELOVL1 Q9BW60 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23733784 0.95 CYP11B1 (0.51) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL23733899 0.88 KDM4E (0.59) CYP19A1CYP1A2CYP3A4ALDH1A1KDM4E
SCHEMBL23370644 0.88 CYP19A1 (0.62) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL10057497 0.88 CYP19A1 (0.62) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL18327513 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL19486738 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL18327644 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL19486745 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL18327578 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6
SCHEMBL19486735 0.86 CYP19A1 (0.61) CYP19A1CYP1A2CYP3A4ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-24 US disclosed
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-11088331-B2 2021-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 CYP19A1 382/4885CYP1A2 61/4885CYP3A4 15/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 CYP19A1 382/4885CYP1A2 61/4885CYP3A4 15/4885
US-11088331-B2 DDT, PPOX, DBF4 CYP19A1 564/4885CYP1A2 73/4885CYP3A4 12/4885
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME DDT, PPOX, LEF1 CYP19A1 382/4885CYP1A2 61/4885CYP3A4 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.