SCHEMBL23733784

SCHEMBL23733784

Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc(-c5cccnc5)c4)cc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.51
CYP11B2 P19099 4/20 0.51
CYP19A1 P11511 3/20 0.51
CYP17A1 P05093 2/20 0.51
MKNK1 Q9BUB5 3/20 0.49
MKNK2 Q9HBH9 3/20 0.49
MEN1 O00255 1/20 0.49
PSIP1 O75475 1/20 0.49
AXL P30530 1/20 0.49
CYP2A6 P11509 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
ALDH1A1 P00352 1/20 0.48
KMO O15229 1/20 0.47
ABL1 P00519 1/20 0.47
BCR P11274 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23733880 0.95 CYP19A1 (0.50) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL26077645 0.90 CYP11B2 (0.58) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL19238745 0.88 CYP19A1 (0.61) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL23733894 0.87 HPGDS (0.53) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL23733899 0.87 KDM4E (0.59) CYP19A1MEN1CYP1A2CYP3A4ALDH1A1
SCHEMBL18327447 0.87 CYP19A1 (0.59) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL18327354 0.87 CYP19A1 (0.59) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL19039944 0.87 CYP19A1 (0.59) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL21982129 0.87 CYP19A1 (0.59) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1
SCHEMBL18327648 0.85 CYP19A1 (0.57) CYP11B1CYP11B2CYP19A1CYP17A1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-24 US disclosed
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-11088331-B2 2021-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 CYP11B1 494/4885CYP11B2 354/4885CYP19A1 382/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 CYP11B1 494/4885CYP11B2 354/4885CYP19A1 382/4885
US-11088331-B2 DDT, PPOX, DBF4 CYP11B1 506/4885CYP11B2 295/4885CYP19A1 564/4885
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME DDT, PPOX, LEF1 CYP11B1 494/4885CYP11B2 354/4885CYP19A1 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.