Sugi Predict

Sugi Predict / Compounds / SCHEMBL23733899

SCHEMBL23733899

SCHEMBL23733899

Fc1ccc(-c2nc(-c3ccc(-c4ccc(-c5ccc(-c6ccccc6)cc5)cc4)cc3)nc(-c3cccnc3)n2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.59
▸ MAPT P10636 4/20 0.59
▸ HSD17B10 Q99714 4/20 0.59
▸ CYP1A2 P05177 4/20 0.59
▸ CYP3A4 P08684 4/20 0.59
▸ HPGD P15428 3/20 0.59
▸ TSHR P16473 3/20 0.59
▸ CYP2C19 P33261 2/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ ALDH1A1 P00352 4/20 0.55
▸ RAB9A P51151 3/20 0.55
▸ TP53 P04637 3/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.55
▸ NPC1 O15118 2/20 0.55
▸ POLB P06746 1/20 0.54
▸ CLK4 Q9HAZ1 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ USP2 O75604 1/20 0.52
▸ PDE5A O76074 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920519 0.89 ALDH1A1 (0.61) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL23733880 0.88 CYP19A1 (0.50) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL19039937 0.87 CYP2A6 (0.62) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL17944660 0.87 CYP2A6 (0.62) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL2254917 0.87 CYP2A6 (0.62) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL5590400 0.87 ALDH1A1 (0.64) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL5590272 0.87 ALDH1A1 (0.64) KDM4EMAPTHSD17B10CYP1A2CYP3A4
SCHEMBL23733818 0.85 DPP4 (0.54) KDM4EMAPTHPGDMAPK1ALDH1A1
SCHEMBL23733848 0.85 DPP4 (0.54) KDM4EMAPTHPGDMAPK1ALDH1A1
SCHEMBL23733835 0.85 DPP4 (0.54) KDM4EMAPTHPGDMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 — — US disclosed
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 — — US disclosed
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-24 — — US disclosed
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 — — US disclosed
US-11088331-B2 — — 2021-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 KDM4E 2929/4885MAPT 2315/4885HSD17B10 1237/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 KDM4E 2929/4885MAPT 2315/4885HSD17B10 1237/4885
US-11088331-B2 — DDT, PPOX, DBF4 KDM4E 3294/4885MAPT 2126/4885HSD17B10 1543/4885
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME DDT, PPOX, LEF1 KDM4E 2929/4885MAPT 2315/4885HSD17B10 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.