Water

Water

SCHEMBL2373926

C[SiH](C)O[SiH3].O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20752 0.95
SCHEMBL9501082 0.95
SCHEMBL1505903 0.90
SCHEMBL16165910 0.90
Ammonia Solution, Strong SCHEMBL9183430 0.90
SCHEMBL10320028 0.90
SCHEMBL16671452 0.90
SCHEMBL2734527 0.90
SCHEMBL18886747 0.90
Hydrochloric Acid SCHEMBL8182468 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1656255-B Acid plating bath and method for the electolytic deposition of satin nickel deposits ATOTECH DEUTSCHLAND GMBH 2010-06-16 CN claimed
EP-1513967-B1 ACID PLATING BATH AND METHOD FOR THE ELECTOLYTIC DEPOSITION OF SATIN NICKEL DEPOSITS ATOTECH DEUTSCHLAND GMBH (DE) 2009-07-01 EP claimed
US-7361262-B2 Acid plating bath and method for the electrolytic deposition of satin nickel deposits ATOTECH DEUTSCHLAND GMBH (DE) 2008-04-22 US claimed
CN-1656255-A Acid plating bath and method for the electolytic deposition of satin nickel deposits ATOTECH DEUTSCHLAND GMBH (DE) 2005-08-17 CN claimed
US-20050150774-A1 Contains quarternary ammonium compound and polyether with strongly hydrophobic side chain; long periods of operation or heating and cooling cycles; gloss finish; reduced sensitivity to wetting agents ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2005-07-14 US claimed
EP-1513967-A2 ACID PLATING BATH AND METHOD FOR THE ELECTOLYTIC DEPOSITION OF SATIN NICKEL DEPOSITS ATOTECH Deutschland GmbH (DE) 2005-03-16 EP claimed
WO-2003100137-A2 ACID PLATING BATH AND METHOD FOR THE ELECTOLYTIC DEPOSITION OF SATIN NICKEL DEPOSITS ATOTECH DEUTSCHLAND GMBH (DE) 2003-12-04 WO claimed
CN-113710329-B Personal care compositions 高露洁-棕榄公司 2024-04-05 CN disclosed
CN-102961266-B Skin surface paint and greasy dirt isolation film and preparation method thereof LARRY XIAMEN TECHNOLOGY CO LTD 2014-07-02 CN disclosed
CN-102961266-A Skin surface paint and greasy dirt isolation film and preparation method thereof LARRY XIAMEN TECHNOLOGY CO LTD 2013-03-13 CN disclosed
US-20120134947-A1 ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING COOLING SENSATION EFFECTS AND METHODS FOR MAKING THE SAME THE DIAL CORPORATION (US) 2012-05-31 US disclosed
US-20120135056-A1 ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING PREDETERMINED EFFECTS AND METHODS FOR MAKING THE SAME THE DIAL CORPORATION (US) 2012-05-31 US disclosed
US-8048406-B2 Antiperspirant THE DIAL CORPORATION (US) 2011-11-01 US disclosed
US-20020155077-A1 Personal care product Henkel IP & Holding GmbH (DE) 2002-10-24 US disclosed
EP-1082387-A1 EMULSION RUBBER MIXTURES CONTAINING HYDROPHOBIC-RENDERED OXIDE OR SILICATE TYPE FILLERS AND THEIR USE FOR PRODUCING TIRES BAYER AG (DE) 2001-03-14 EP disclosed
EP-0952185-A1 Compositions containing rubbers and activated and hydrophobised oxidic and siliceous fillers and process for preparation BAYER AG (DE) 1999-10-27 EP disclosed
WO-1999051673-A1 EMULSION RUBBER MIXTURES CONTAINING HYDROPHOBIC-RENDERED OXIDE OR SILICATE TYPE FILLERS AND THEIR USE FOR PRODUCING TIRES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-14 WO disclosed
EP-0890600-A1 Process for preparing rubber compositions with fillers BAYER AG (DE) 1999-01-13 EP disclosed
US-5817302-A POLYSILSESQUISILOXANES, COSMETICS GENERAL ELECTRIC COMPANY (US) 1998-10-06 US disclosed
US-5684112-A Low viscosity organofunctionalized siloxysilicates and cosmetic formulations therewith GENERAL ELECTRIC COMPANY (US) 1997-11-04 US disclosed