Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089649 | 0.99 | HPGD (0.49) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL2088037 | 0.99 | HPGD (0.49) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL2088041 | 0.99 | HPGD (0.49) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| Potassium SCHEMBL2089657 | 0.99 | HPGD (0.49) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL956329 | 0.92 | MAOB (0.46) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL955931 | 0.91 | HPGD (0.46) | HPGDMAOBPTPN1NR4A2FFAR1 | |
| SCHEMBL2184379 | 0.90 | MAOB (0.46) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL2184376 | 0.88 | MAOB (0.45) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL1719411 | 0.88 | MAOB (0.45) | HPGDMAOBPTPN1SLC22A12NR4A2 | |
| SCHEMBL2088038 | 0.87 | PTPN1 (0.45) | HPGDMAOBPTPN1SLC22A12NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517109-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | Wellstat Therapeutics Corporation (US) | 2019-07-31 | — | — | EP | claimed |
| EP-2285777-B1 | SYNTHESIS OF 4-[3-(2,6-DIMETHYLBENZYLOXY)PHENYL]-4-OXOBUTANOIC ACID | WELLSTAT THERAPEUTICS CORP (US) | 2016-09-07 | — | — | EP | claimed |
| US-9115072-B2 | Compounds and method for reducing uric acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2015-08-25 | — | — | US | claimed |
| US-8703991-B2 | Synthesis of (phenylalkyloxy)phenyl-oxobutanoic acids | WELLSTAT THERAPEUTICS CORPORATION (US) | 2014-04-22 | — | — | US | claimed |
| US-8664433-B2 | Synthesis of 4-[3-(2,6-dimethylbenzyloxy)phenyl]-4-oxobutanoic acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2014-03-04 | — | — | US | claimed |
| EP-1461323-B1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORP (US) | 2013-10-09 | — | — | EP | claimed |
| US-8552062-B2 | Methods for the treatment of metabolic disorders such as diabetes | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-10-08 | — | — | US | claimed |
| US-20130259850-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-10-03 | — | — | US | claimed |
| US-20130137629-A1 | COMBINATION TREATMENT FOR METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-05-30 | — | — | US | claimed |
| US-8338480-B2 | Combination treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-12-25 | — | — | US | claimed |
| WO-2009151695-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009137381-A1 | SYNTHESIS OF 4-[3-(2,6-DIMETHYLBENZYLOXY)PHENYL]-4-OXOBUTANOIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2009-11-12 | — | — | WO | claimed |
| EP-2056673-A2 | COMBINATION TREATMENT FOR METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2009-05-13 | — | — | EP | claimed |
| EP-2001461-A2 | COMBINATION TREATMENT OF METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2008022267-A2 | COMBINATION TREATMENT FOR METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2007117791-A2 | COMBINATION TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2007-10-18 | — | — | WO | claimed |
| US-7101910-B2 | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2006-09-05 | — | — | US | claimed |
| EP-1461323-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2004-09-29 | — | — | EP | claimed |
| US-20030149107-A1 | Compounds for the treatment of metabolic disorders | PHARMA CINQ, LLC | 2003-08-07 | — | — | US | claimed |
| WO-2002100341-A2 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2002-12-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130259850-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | RCC2, HAX1, SLC10A6 | HPGD 3648/4885MAOB 3406/4885PTPN1 2554/4885 |
| US-20030149107-A1 | Compounds for the treatment of metabolic disorders | GOT2, OAT, CPT1B | HPGD 381/4885MAOB 589/4885PTPN1 4514/4885 |
| US-20130137629-A1 | COMBINATION TREATMENT FOR METABOLIC DISORDERS | DPP8, GLP1R, GPR119 | HPGD 4574/4885MAOB 4778/4885PTPN1 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.