Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.41 |
| ▸ | HTR2A | P28223 | 11/20 | 0.41 |
| ▸ | HTR1A | P08908 | 12/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739535 | 0.89 | DRD2 (0.42) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL23739567 | 0.88 | DRD2 (0.55) | DRD2HTR2AHTR1A | |
| SCHEMBL23739693 | 0.86 | HTR1A (0.44) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL23739525 | 0.86 | DRD2 (0.52) | DRD2HTR2AHTR1A | |
| SCHEMBL23739667 | 0.82 | POLB (0.35) | — | |
| SCHEMBL23739596 | 0.81 | DRD2 (0.48) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL23739929 | 0.81 | DRD2 (0.43) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL23934619 | 0.81 | ALDH1A1 (0.44) | — | |
| SCHEMBL23739905 | 0.80 | DRD2 (0.45) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL24572202 | 0.79 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |