Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373365 | 0.78 | HTT (0.47) | SMN1; SMN2LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL7220977 | 0.72 | RAB9A (0.46) | SMN1; SMN2TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL13503932 | 0.71 | HTT (0.50) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL13503925 | 0.71 | MAPT (0.48) | SMN1; SMN2LMNAALDH1A1POLBMAPT | |
| SCHEMBL13504081 | 0.67 | HTT (0.71) | ALDH1A1MAPTKMT2AHPGDHRH3 | |
| SCHEMBL12431599 | 0.67 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL3153203 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13646643 | 0.67 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL1871362 | 0.67 | RAB9A (0.46) | SMN1; SMN2TDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL13503928 | 0.66 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1HPGDHRH3GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | Aduro Biotech, Inc. (US) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | IL5, IL15, TLR5 | SMN1; SMN2 965/4885LMNA 4410/4885L3MBTL1 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.