Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251367 | 0.91 | MIF (0.41) | MIFTP53TDP1FAAHALDH1A1 | |
| SCHEMBL9752705 | 0.84 | MIF (0.48) | MIFNAAAHTR3AHTR3EHTR3B | |
| SCHEMBL3618228 | 0.81 | MIF (0.40) | MIFTDP1NAAAALDH1A1TSHR | |
| SCHEMBL3628956 | 0.81 | TP53 (0.44) | MIFTP53TDP1FAAHGRIN1 | |
| SCHEMBL6808470 | 0.79 | MIF (0.50) | MIFNAAAHTR3AHTR3EHTR3B | |
| SCHEMBL595251 | 0.78 | TP53 (0.47) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL21248287 | 0.78 | HTR3E (0.51) | MIFHTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23648092 | 0.77 | TP53 (0.42) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL3621874 | 0.76 | MIF (0.41) | MIFTDP1NAAAALDH1A1 | |
| SCHEMBL595016 | 0.76 | TP53 (0.52) | TP53TDP1FAAHALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649325-B2 | Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2023-05-16 | — | — | US | disclosed |
| US-20210246270-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab Sg Pte Ltd. (SG) | 2021-08-12 | — | — | US | disclosed |