Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10317353 | 0.85 | LMNA (0.42) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL313796 | 0.80 | LMNA (0.38) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL2263489 | 0.80 | NR1I2 (0.42) | LMNATSHRALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL5339026 | 0.79 | TSHR (0.47) | TDP1TSHRALDH1A1RXRARXRB | |
| SCHEMBL565221 | 0.77 | LMNA (0.50) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL313331 | 0.77 | TAS2R14 (0.40) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL11670825 | 0.75 | LMNA (0.48) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL5025806 | 0.72 | ALDH1A1 (0.56) | TSHRALDH1A1SMN1; SMN2RXRARXRB | |
| SCHEMBL150334 | 0.72 | LMNA (0.77) | LMNATDP1TSHRALDH1A1NT5E | |
| SCHEMBL22666586 | 0.72 | LMNA (0.45) | LMNATDP1TSHRALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1913032-B1 | SULFONATED BLOCK COPOLYMERS, METHOD FOR MAKING SAME, AND VARIOUS USES FOR SUCH BLOCK COPOLYMERS | KRATON POLYMERS RES BV (NL) | 2011-09-21 | — | — | EP | claimed |