Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705194 | 0.82 | DGAT1 (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL6379683 | 0.82 | DGAT1 (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL27557003 | 0.80 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL3808762 | 0.80 | CRBN (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL3808765 | 0.80 | CRBN (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL601561 | 0.78 | MAOA (0.36) | DGAT1CA12CA14MAOAMAOB | |
| SCHEMBL601562 | 0.78 | MAOA (0.36) | DGAT1CA12CA14MAOAMAOB | |
| SCHEMBL3728300 | 0.78 | MAOA (0.36) | DGAT1CA12CA14MAOAMAOB | |
| SCHEMBL26464845 | 0.78 | DGAT1 (0.33) | DGAT1MAOAMAOB | |
| SCHEMBL3994044 | 0.77 | CA1 (0.35) | DGAT1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155612-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021155791-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-08-12 | — | — | WO | disclosed |