Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23746404 | 0.80 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL28705194 | 0.74 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL6379683 | 0.74 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL28101880 | 0.74 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL3808765 | 0.73 | CRBN (0.34) | DGAT1 | |
| SCHEMBL3808762 | 0.73 | CRBN (0.34) | DGAT1 | |
| SCHEMBL508234 | 0.72 | NOS1 (0.33) | — | |
| SCHEMBL2341507 | 0.72 | F2 (0.35) | — | |
| SCHEMBL601561 | 0.72 | MAOA (0.36) | DGAT1 | |
| SCHEMBL3728300 | 0.72 | MAOA (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1332964-C | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| CN-1656107-A | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2005-08-17 | — | — | CN | disclosed |