Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101687 | 0.80 | RAB9A (0.57) | MEN1KMT2AHPGDRAB9AERCC1 | |
| SCHEMBL23747697 | 0.79 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2AHPGDGAA | |
| SCHEMBL31029198 | 0.74 | GAA (0.45) | MEN1KMT2AGAACYP1A2CYP2C9 | |
| SCHEMBL15858059 | 0.72 | LMNA (0.51) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL26548227 | 0.71 | LMNA (0.56) | L3MBTL1KMT2ADRD3KCNH2GAA | |
| SCHEMBL15858005 | 0.71 | ALDH1A1 (0.53) | L3MBTL1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL12361201 | 0.71 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2ADRD3KCNH2 | |
| SCHEMBL23747349 | 0.71 | RAB9A (0.48) | MEN1KMT2AHPGDCYP1A2CYP2C19 | |
| SCHEMBL23747348 | 0.70 | CYP1A2 (0.44) | MEN1KMT2AHPGDCYP1A2CYP2C19 | |
| SCHEMBL23747464 | 0.70 | RAB9A (0.56) | MEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |