Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CLPP | Q16740 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101837 | 0.80 | CHRM1 (0.62) | CACNA1GCHRM1HTR2AMCHR1MEN1 | |
| SCHEMBL23747740 | 0.79 | L3MBTL1 (0.40) | L3MBTL1MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24024157 | 0.77 | NOD1 (0.62) | CACNA1GMEN1CYP1A2CYP2C9RAB9A | |
| SCHEMBL31043587 | 0.74 | CACNA1G (0.48) | CACNA1GMEN1RAB9AKMT2AGAA | |
| SCHEMBL26100896 | 0.73 | CHRM1 (0.53) | CACNA1GCHRM1HTR2AMCHR1MEN1 | |
| SCHEMBL3401709 | 0.71 | LMNA (0.60) | ALOX12SLC2A1CA2MCHR1SIGMAR1 | |
| SCHEMBL12642576 | 0.71 | PIK3CD (0.47) | L3MBTL1CA12CA2CA9MCHR1 | |
| SCHEMBL221818 | 0.71 | MC4R (0.58) | SLC2A1MCHR1SIGMAR1DRD4MEN1 | |
| SCHEMBL23747465 | 0.71 | HTR2A (0.48) | CHRM1HTR2AMCHR1MEN1RAB9A | |
| SCHEMBL23747463 | 0.70 | CHRM1 (0.45) | L3MBTL1CACNA1GCHRM1HTR2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |