Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ARNT | P27540 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747861 | 0.88 | MAPT (0.42) | MAPTALDH1A1GAAEPAS1VEGFA | |
| SCHEMBL18796268 | 0.87 | TLR8 (0.48) | TLR8MAPTALDH1A1GAAPIN1 | |
| SCHEMBL18796231 | 0.82 | PIN1 (0.46) | TLR8MAPTALDH1A1GAAEPAS1 | |
| SCHEMBL23747874 | 0.80 | TLR8 (0.40) | TLR8ALDH1A1CNR1CNR2CYP3A4 | |
| SCHEMBL18796279 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1GAAPIN1CYP3A4 | |
| SCHEMBL18796214 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1GAAPIN1CYP3A4 | |
| SCHEMBL11497261 | 0.72 | HPGD (0.58) | TLR8ALDH1A1GAAEPAS1PIN1 | |
| SCHEMBL23747871 | 0.72 | L3MBTL1 (0.37) | ALDH1A1CNR1CNR2CYP3A4PPARG | |
| SCHEMBL23747866 | 0.72 | L3MBTL1 (0.37) | MAPTALDH1A1GAACNR1CNR2 | |
| SCHEMBL10482222 | 0.72 | TLR8 (0.60) | TLR8MAPTALDH1A1EPAS1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | claimed |