Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23748272 | 0.80 | PRKCZ (0.46) | ALDH1A1L3MBTL1PRKCZLMNACYP3A4 | |
| SCHEMBL1095401 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1CYP2C19CYP3A4 | |
| SCHEMBL421953 | 0.73 | ALDH1A1 (0.35) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL9282939 | 0.71 | LMNA (0.46) | ALDH1A1L3MBTL1LMNACYP3A4HTT | |
| SCHEMBL9283161 | 0.68 | NSD2 (0.41) | ALDH1A1L3MBTL1LMNACYP2C19HTT | |
| SCHEMBL23748207 | 0.68 | PRKCZ (0.43) | ALDH1A1L3MBTL1PRKCZLMNACYP3A4 | |
| SCHEMBL3067123 | 0.65 | PRKCZ (0.45) | ALDH1A1L3MBTL1PRKCZLMNACYP3A4 | |
| SCHEMBL11909148 | 0.64 | PKM (0.42) | ALDH1A1L3MBTL1CYP3A4HTTMAPT | |
| SCHEMBL30865056 | 0.64 | PKM (0.42) | ALDH1A1L3MBTL1CYP3A4HTTMAPT | |
| SCHEMBL30865055 | 0.64 | PKM (0.42) | ALDH1A1L3MBTL1CYP3A4HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | Janssen Biopharma, Inc. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3864020-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen BioPharma, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-113195502-A | Macrocyclic influenza endonuclease inhibitors | 詹森生物制药有限公司 | 2021-07-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | ACE, PNP, FEN1 | ALDH1A1 2073/4885L3MBTL1 2124/4885PRKCZ 1812/4885 |
| US-11312727-B1 | Macrocyclic flu endonuclease inhibitors | ACE, FEN1, PNP | ALDH1A1 1487/4885L3MBTL1 3042/4885PRKCZ 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.