Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886542 | 0.85 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL12940192 | 0.79 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL15543215 | 0.79 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL18115648 | 0.78 | ALDH1A1 (0.58) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL24421814 | 0.76 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL569815 | 0.76 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL11951644 | 0.76 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL11951588 | 0.76 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1GRIN2B | |
| SCHEMBL15544188 | 0.75 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL23748780 | 0.75 | ALDH1A1 (0.41) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |