Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829636 | 0.81 | ALOX5 (0.46) | ALDH1A1ALOX5GAAKDM4EMAPT | |
| SCHEMBL9829630 | 0.81 | ALOX5 (0.46) | ALDH1A1ALOX5GAAKDM4EMAPT | |
| SCHEMBL7505420 | 0.72 | ALDH1A1 (0.74) | ALDH1A1F2RPOLBGAAKMT2A | |
| SCHEMBL24521599 | 0.70 | MEN1 (0.59) | ALDH1A1F2RKMT2ACYP2C19CYP3A4 | |
| SCHEMBL2364652 | 0.70 | ALDH1A1 (0.38) | ALDH1A1POLBKMT2AMAPTHPGD | |
| SCHEMBL2410747 | 0.69 | POLQ (0.42) | ALDH1A1POLBGAAKMT2AKDM4E | |
| SCHEMBL3261991 | 0.69 | POLQ (0.42) | ALDH1A1POLBGAAKDM4EHPGD | |
| SCHEMBL4214258 | 0.69 | ALDH1A1 (0.51) | ALDH1A1F2RGAAKMT2AKDM4E | |
| SCHEMBL4214268 | 0.69 | ALDH1A1 (0.51) | ALDH1A1F2RGAAKMT2AKDM4E | |
| SCHEMBL12286073 | 0.67 | ALOX5 (0.51) | ALDH1A1ALOX5GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | claimed |