Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185066 | 0.77 | — | — | |
| SCHEMBL27816961 | 0.73 | L3MBTL1 (0.45) | LMNAF2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL732742 | 0.73 | MMP1 (0.53) | LMNAF2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5229371 | 0.72 | — | — | |
| SCHEMBL7802262 | 0.70 | F2 (0.45) | LMNAF2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27736514 | 0.70 | KMT2A (0.48) | LMNAF2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25220465 | 0.69 | KMT2A (0.53) | LMNAF2KMT2AMAPTTDP1 | |
| SCHEMBL29154627 | 0.69 | MEN1 (0.58) | KMT2AMAPTTDP1MEN1 | |
| SCHEMBL175110 | 0.69 | HPGDS (0.53) | LMNAKMT2AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL5551848 | 0.68 | LMNA (0.64) | LMNAF2KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |