Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749132 | 0.97 | GABRA1 (0.43) | GABRA1GABRB2CDK1CDK2ELANE | |
| Potassium Ion SCHEMBL23749101 | 0.84 | GABRA1 (0.42) | GABRA1GABRB2ELANEATMCTSG | |
| SCHEMBL11658387 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2ELANEATMCTSG | |
| Ammonia Solution, Strong SCHEMBL23749160 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2CDK1CDK2ELANE | |
| Potassium Ion SCHEMBL23749139 | 0.78 | HTR2A (0.33) | GABRA1GABRB2 | |
| SCHEMBL27447467 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2ELANEATMCTSG | |
| SCHEMBL2743774 | 0.75 | GABRA1 (0.62) | GABRA1GABRB2ELANECTSGGAA | |
| Potassium Ion SCHEMBL23749105 | 0.75 | GABRA1 (0.39) | GABRA1GABRB2P2RY2P2RY4 | |
| Potassium Ion SCHEMBL23749108 | 0.75 | FUT7 (0.33) | ALDH1A1 | |
| SCHEMBL23749135 | 0.74 | HTR2A (0.33) | P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864963-A1 | OILY SUSPENSION AGROCHEMICAL COMPOSITION | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-08-18 | — | — | EP | disclosed |