SCHEMBL23749239

SCHEMBL23749239

CC(C)(C)OC(=O)c1cccc2c1C(=O)OC21c2ccc(O[Si](C)(C)C(C)(C)C)cc2[Si](C)(C)c2cc(O[Si](C)(C)C(C)(C)C)ccc21

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23749243 0.87 MEN1 (0.45) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL23749244 0.87 CA12 (0.34) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL23749238 0.83 HSD11B1 (0.36) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL18493254 0.82 MEN1 (0.34) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL18493240 0.79 CYP3A4 (0.46) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL26733666 0.73 MEN1 (0.32) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL31430766 0.73 GSTP1 (0.32) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL23753389 0.73 GSTP1 (0.32) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL23749241 0.72 FTO (0.53) MEN1USP2ALDH1A1LMNAMAPT
SCHEMBL23749242 0.72 MAPT (0.39) MEN1USP2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230104281-A1 FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2023-04-06 US disclosed
EP-3865544-A1 FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-08-18 EP disclosed