Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749243 | 0.89 | MEN1 (0.45) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL23749239 | 0.87 | MEN1 (0.33) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL23749242 | 0.83 | MAPT (0.39) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL20262989 | 0.82 | LMNA (0.35) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL23749237 | 0.81 | PDK2 (0.33) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL19849703 | 0.78 | CYP3A4 (0.47) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL19844012 | 0.73 | LMNA (0.44) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL23749241 | 0.73 | FTO (0.53) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL23749240 | 0.71 | ALDH1A1 (0.43) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL23749238 | 0.70 | HSD11B1 (0.36) | MEN1USP2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865544-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-08-18 | — | — | EP | disclosed |