Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELPLG | Q14242 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835507 | 0.77 | CTSK (0.39) | CYP2C9CYP2C19AKR1C3AKR1C2MMP2 | |
| SCHEMBL9294341 | 0.76 | KCNQ2 (0.53) | AKR1C3AKR1C2KCNQ2MAPTPPARG | |
| SCHEMBL1679693 | 0.74 | CYP2C19 (0.43) | CYP2C9CYP2C19MMP9PPARGPPARA | |
| SCHEMBL20520340 | 0.73 | PPARG (0.49) | AKR1C3AKR1C2KCNQ2MAPTPPARG | |
| SCHEMBL6909558 | 0.70 | MEN1 (0.63) | AKR1C3AKR1C2KCNQ2CYP3A4MEN1 | |
| SCHEMBL1489632 | 0.70 | KCNQ2 (0.50) | KCNQ2CYP3A4MEN1KMT2A | |
| SCHEMBL30821928 | 0.70 | KCNQ2 (0.50) | KCNQ2CYP3A4MEN1KMT2A | |
| SCHEMBL1742115 | 0.69 | POLB (0.58) | CYP2C9CYP2C19AKR1C3AKR1C2KCNQ2 | |
| SCHEMBL7711076 | 0.69 | POLB (0.58) | CYP2C9CYP2C19AKR1C3AKR1C2KCNQ2 | |
| SCHEMBL16075922 | 0.69 | POLB (0.58) | CYP2C9CYP2C19AKR1C3AKR1C2KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834378-B | Biphenyl-substituted cyclic keto-enols | 拜耳知识产权有限责任公司 | 2016-07-06 | — | — | CN | disclosed |
| US-8901038-B2 | Biphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2014-12-02 | — | — | US | disclosed |
| US-20110230346-A1 | Biphenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230346-A1 | Biphenyl-Substituted Cyclic Ketoenols | KCNE1, KDM4E, PIKFYVE | SELPLG 4818/4885CYP2C9 243/4885CYP2C19 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.