Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | PON1 | P27169 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763735 | 0.88 | PGR (0.30) | PGRRORARORCRORB | |
| SCHEMBL23763736 | 0.87 | PIK3CD (0.33) | ALDH1A1NPSR1RXFP1PGRRORA | |
| SCHEMBL23763560 | 0.85 | ALDH1A1 (0.34) | ALDH1A1NPSR1RXFP1PGRRORA | |
| SCHEMBL23763559 | 0.82 | PON1 (0.33) | PON1 | |
| SCHEMBL23763591 | 0.80 | TNF (0.32) | PGRRORARORCRORBKIF11 | |
| SCHEMBL23763499 | 0.79 | ALDH1A1 (0.39) | ALDH1A1NPSR1PGRRORARORC | |
| SCHEMBL23763731 | 0.79 | HTR1D (0.33) | PGRRORARORCRORB | |
| SCHEMBL23763588 | 0.79 | PIK3CD (0.32) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL23763557 | 0.78 | HTR1D (0.34) | PGRRORARORCRORBKIF11 | |
| SCHEMBL23763733 | 0.77 | PLK4 (0.36) | ALDH1A1PGRRORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |