SCHEMBL23763560

SCHEMBL23763560

CC(C)(C)c1ccc2c(c1)c1c3c4c(c5cc(C(C)(C)C)ccc5n4c4nc5cc6c(cc5n34)oc3ccccc36)c3c1n2c1nc2cc4c(cc2n31)oc1ccccc14

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
AHR P35869 1/20 0.32
HPGD P15428 1/20 0.32
PGR P06401 1/20 0.31
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31
MAOA P21397 1/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23763559 0.93 PON1 (0.33)
SCHEMBL23763514 0.85 ALDH1A1 (0.32) ALDH1A1NPSR1RXFP1PGRRORA
SCHEMBL23763735 0.83 PGR (0.30) PGRRORARORCRORB
SCHEMBL23763594 0.83
SCHEMBL23763736 0.83 PIK3CD (0.33) ALDH1A1NPSR1RXFP1PGRRORA
SCHEMBL23763588 0.81 PIK3CD (0.32) ALDH1A1PGRRORARORCRORB
SCHEMBL23763557 0.80 HTR1D (0.34) PGRRORARORCRORBKIF11
SCHEMBL23763499 0.79 ALDH1A1 (0.39) ALDH1A1NPSR1HPGDPGRRORA
SCHEMBL23763731 0.79 HTR1D (0.33) PGRRORARORCRORB
SCHEMBL23763733 0.77 PLK4 (0.36) ALDH1A1PGRRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865486-A1 HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-18 EP disclosed