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SCHEMBL23763583

SCHEMBL23763583

Cc1cc(C)c(-c2cccc3c4c5c6c(c7cccc(-c8c(C)cc(Cc9cccc%10c9nc9n%10c%10c%11c%12c(-c%13c(C)cccc%13C)cccc%12n%12c%11c(c%11c%13c(-c%14c(C)cccc%14C)cccc%13n9c%11%10)n9c%10ccccc%10nc9%12)cc8C)c7n6c6nc7ccccc7n56)c5c4n(c23)c2nc3ccccc3n52)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FLT3 P36888 1/20 0.32
▸ CRHR1 P34998 2/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23763393 0.81 MAPT (0.40) FLT3TP53MAPT
SCHEMBL23763584 0.81 MAPT (0.39) FLT3TP53MAPT
SCHEMBL23763563 0.73 CRHR1 (0.41) FLT3CRHR1MAPT
SCHEMBL23763634 0.71 MAPT (0.38) FLT3TP53MAPT
SCHEMBL23763589 0.69 SMN1; SMN2 (0.33) FLT3TP53MAPT
SCHEMBL23763392 0.67 HPGD (0.39) FLT3TP53MAPT
SCHEMBL23763632 0.66 SRC (0.38) FLT3TP53MAPT
SCHEMBL23763633 0.65 ALDH1A1 (0.40) FLT3TP53MAPT
SCHEMBL24601592 0.63 CYP1A2 (0.38) FLT3CRHR1MAPT
SCHEMBL24601535 0.62 CYP1A2 (0.40) CRHR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865486-A1 HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-18 — — EP disclosed