Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145214 | 0.80 | NPC1 (0.44) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL22939858 | 0.79 | CYP1A2 (0.56) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL22830378 | 0.78 | NR4A2 (0.39) | RAB9ANPC1HPGDSMN1; SMN2PKM | |
| SCHEMBL12869882 | 0.78 | LMNA (0.55) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL29255118 | 0.77 | MAPT (0.51) | RAB9ANPC1HPGDSMN1; SMN2PKM | |
| SCHEMBL23582397 | 0.75 | ROCK2 (0.51) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL4113212 | 0.75 | CYP4F2 (0.76) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL23582659 | 0.74 | RAB9A (0.47) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL1428025 | 0.74 | LMNA (0.62) | CYP4F2CYP4A11RAB9ANPC1HPGD | |
| SCHEMBL27694530 | 0.73 | RAB9A (0.49) | CYP4F2CYP4A11RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160127-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-08-19 | — | — | WO | disclosed |