Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265678 | 0.81 | CA2 (0.58) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL112488 | 0.79 | CYP4F2 (0.66) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL26971309 | 0.78 | HSD17B1 (0.52) | RAB9ANPC1ALDH1A1HSP90AB1SMN1; SMN2 | |
| SCHEMBL12869882 | 0.78 | LMNA (0.55) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL7646563 | 0.77 | CYP4F2 (0.63) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL27517466 | 0.77 | CYP4F2 (0.63) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL18818444 | 0.77 | CA1 (0.59) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27178839 | 0.77 | RAB9A (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15710323 | 0.76 | HSP90AB1 (0.47) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL30106072 | 0.76 | HSP90AB1 (0.47) | RAB9ANPC1ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094827-B | Benzene compound having two or more substituents | DAIICHI SANKYO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101094827-A | Benzene compound having two or more substituents | SANKYO CO (JP) | 2007-12-26 | — | — | CN | disclosed |