Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770437 | 0.75 | NOS3 (0.35) | DPP4ADORA2A | |
| SCHEMBL19925036 | 0.74 | ALOX5AP (0.34) | CTSDBACE1ADORA2A | |
| SCHEMBL29464345 | 0.74 | ALOX5AP (0.34) | CTSDBACE1ADORA2A | |
| SCHEMBL19968759 | 0.74 | BACE1 (0.47) | DPP4CTSDBACE1ADORA2A | |
| SCHEMBL29464888 | 0.74 | BACE1 (0.47) | DPP4CTSDBACE1ADORA2A | |
| SCHEMBL23770590 | 0.68 | ADORA2A (0.35) | DPP4CTSDBACE1ADORA2A | |
| SCHEMBL23770629 | 0.68 | PTPN1 (0.32) | DPP4CTSDBACE1ADORA2A | |
| SCHEMBL19968754 | 0.67 | HSD11B1 (0.38) | CTSDBACE1ADORA2A | |
| SCHEMBL29464324 | 0.67 | HSD11B1 (0.38) | CTSDBACE1ADORA2A | |
| SCHEMBL19925031 | 0.67 | PIK3CD (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |