Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 5/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770471 | 0.86 | SOS1 (0.34) | SOS1 | |
| SCHEMBL23770452 | 0.82 | PDE10A (0.34) | — | |
| SCHEMBL23770564 | 0.82 | SOS1 (0.40) | SOS1 | |
| SCHEMBL19925199 | 0.82 | KIF18A (0.36) | SOS1RAF1BRAF | |
| SCHEMBL23770463 | 0.80 | BTK (0.34) | RAF1BRAF | |
| SCHEMBL23770592 | 0.80 | ADORA2A (0.32) | — | |
| SCHEMBL23770466 | 0.79 | CYP1A2 (0.37) | SOS1 | |
| SCHEMBL23770770 | 0.79 | ADRB2 (0.38) | SOS1RAF1BRAF | |
| SCHEMBL23770433 | 0.78 | PDE10A (0.36) | — | |
| SCHEMBL23770447 | 0.78 | SOS1 (0.34) | SOS1RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |