SCHEMBL237802

SCHEMBL237802

CC(C)Cc1ccc(-c2ccc(OC(=O)Oc3ccc(-c4ccc(CC(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.52
PTGS1 P23219 3/20 0.47
CXCR1 P25024 3/20 0.47
CXCR2 P25025 3/20 0.47
LMNA P02545 2/20 0.47
CYP2C9 P11712 2/20 0.47
AKR1C3 P42330 2/20 0.47
AKR1C2 P52895 2/20 0.47
ALB P02768 1/20 0.47
ESR1 P03372 1/20 0.47
ALOX5 P09917 1/20 0.47
RARB P10826 1/20 0.47
ADRB3 P13945 1/20 0.47
NFKB1 P19838 1/20 0.47
HTR2A P28223 1/20 0.47
NR1I3 Q14994 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
CXCL8 P10145 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237613 0.94 PTGS2 (0.56) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL248142 0.88 PTGS2 (0.51) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL159833 0.81 PTGS2 (0.55) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21517639 0.81 PTGS2 (0.55) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL6273093 0.81 ELANE (0.58) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL23824811 0.81 PPARG (0.49) ESR1ADRB3PPARGPPARA
SCHEMBL9951576 0.81 PPARG (0.49) ESR1ADRB3PPARGPPARA
SCHEMBL20040901 0.80 PTGS2 (0.54) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL18531358 0.80 SENP1 (0.45) PTGS2LMNAAKR1C2ESR1ADRB3
SCHEMBL19485876 0.80 SMN1; SMN2 (0.51) PTGS2LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
EP-4493388-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-01-22 EP disclosed
CN-114650915-B Layer structure with modified structure and production thereof 科思创德国股份有限公司 2024-05-31 CN disclosed
CN-117203063-A Method for locally coloring plastic parts using solid dyes in a color carrier layer 科思创德国股份有限公司 2023-12-08 CN disclosed
WO-2023174814-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2023-09-21 WO disclosed
CN-111542565-B Plastic film with reduced UV activity 科思创德国股份有限公司 2023-08-22 CN disclosed
CN-114746488-A Films with special properties 科思创知识产权两合公司 2022-07-12 CN disclosed
CN-114650915-A Layer structure with modified structure and production thereof 科思创知识产权两合公司 2022-06-21 CN disclosed
CN-108778766-B Method for partially dyeing plastic parts 科思创德国股份有限公司 2021-12-31 CN disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
US-6767986-B2 A LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS PREPARED AND A SECOND STAGE WHERE THE LOW MOLECULAR WEIGHT ALIPHATIC POLYCARBONATE IS CONDENSED WITH DIARYL CARBONATE IN A MELT TRANSESTERIFICATION PROCESS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US disclosed
US-20040143088-A1 Method for producing polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2004-07-22 US disclosed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-20040030090-A1 Polycarbonates, polyester carbonates and polyesters with special branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
US-6646099-B2 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
US-20030204042-A1 Production and use of high molecular weight aliphatic polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-10-30 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed