Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237613 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL159833 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL21517639 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9577301 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL577068 | 0.80 | ESR1 (0.57) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL237802 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| Hydrochloric Acid SCHEMBL25299360 | 0.79 | ESR1 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL19971604 | 0.79 | ESR1 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL248142 | 0.79 | PTGS2 (0.51) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL27655928 | 0.79 | ESR1 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154965-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-08 | — | — | EP | disclosed |
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |