SCHEMBL237868

SCHEMBL237868

CC(C)(C#N)SC(=S)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.36
MAPT P10636 3/20 0.36
HSP90AA1 P07900 1/20 0.35
LMNA P02545 3/20 0.35
RAB9A P51151 2/20 0.35
EPHX1 P07099 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
TSHR P16473 2/20 0.32
CTSL P07711 1/20 0.32
KMT2A Q03164 3/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26489562 0.84 ALDH1A1 (0.33) ALDH1A1MAPTHSP90AA1LMNARAB9A
SCHEMBL17562113 0.84 ALDH1A1 (0.33) ALDH1A1MAPTHSP90AA1LMNARAB9A
SCHEMBL15282106 0.82 CYP2D6 (0.33) ALDH1A1MAPTHSP90AA1LMNARAB9A
SCHEMBL16107022 0.81 CA2 (0.40) ALDH1A1MAPTLMNAHTTSMN1; SMN2
SCHEMBL28537192 0.81 MEN1 (0.37) ALDH1A1MAPTLMNARAB9AMAPK1
SCHEMBL3383990 0.81 LMNA (0.38) ALDH1A1MAPTHSP90AA1LMNARAB9A
SCHEMBL13933709 0.80 PDE4A (0.41) ALDH1A1MAPTRAB9ANPSR1PDE4A
SCHEMBL236901 0.79 ALDH1A1 (0.41) ALDH1A1MAPTHSP90AA1LMNARAB9A
SCHEMBL14329435 0.79 EPHX2 (0.36) HPGDSMN1; SMN2
SCHEMBL21482392 0.79 LMNA (0.33) ALDH1A1MAPTLMNARAB9ACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
CN-119708392-A Thermal response micelle and crosslinked micelle as well as preparation methods and applications thereof 中国科学院兰州化学物理研究所 2025-03-28 CN claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
CN-119549099-A Production system capable of accurately regulating and controlling molecular weight and distribution of carbon fiber stock solution 浙江精工集成科技股份有限公司 2025-03-04 CN claimed
EP-4490209-A1 RANDOM HETEROPOLYMER EXCIPIENTS FOR HIGH PROTEIN CONCENTRATION FORMULATIONS Genentech Inc. (US) 2025-01-15 EP claimed
US-20240426835-A1 Random Heteropolymer Excipients For High Protein Concentration Formulations GENENTECH, INC. (US) 2024-12-26 US claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
WO-2024233709-A2 FLUORINATED COPOLYMER BOTTLEBRUSHES FOR OPTICAL APPLICATIONS DUKE UNIVERSITY (US) 2024-11-14 WO claimed
CN-118580420-A Aqueous suspension living radical polymerization method of polyacrylonitrile with narrow molecular weight distribution 山东国泰大成科技有限公司 2024-09-03 CN claimed
EP-3919408-B1 CAPS WITH SAFETY FUNCTION AGAINST OVERPRESSURE LANXESS DEUTSCHLAND GMBH (DE) 2024-03-13 EP claimed
EP-1950232-A1 Process for the preparation of graft copolymers by Reversible Addition Fragmentation Chain Transfer (RAFT) and Ring Opening Polymerisation (ROP) Polymers Australia PTY Limited (AU) 2008-07-30 EP claimed
US-20080071003-A1 Method for Producing Molecularly Imprinted Polymers UNIVERSITY OF DORTMUND INFU (DE) 2008-03-20 US claimed
EP-1781711-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS University of Dortmund Infu (DE) 2007-05-09 EP claimed
WO-2006128644-A1 POLYMER COATING AND FUNCTIONALIZATION OF SOLID SURFACES PIRRI GIOVANNA (IT) 2006-12-07 WO claimed
EP-1383828-A4 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION BIO LAYER PTY LTD (AU) 2006-10-04 EP claimed
WO-2006004536-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS UNIVERSITY OF DORTMUND INFU (DE) 2006-01-12 WO claimed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US claimed
EP-1383828-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION Polymerat Pty Ltd (AU) 2004-01-28 EP claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA ALDH1A1 1404/4885MAPT 1187/4885HSP90AA1 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.