Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 8/20 | 0.34 |
| ▸ | EDNRA | P25101 | 8/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237431 | 0.81 | TSHR (0.45) | TSHRALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL236553 | 0.73 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL237894 | 0.73 | THRB (0.46) | TSHRTHRBALDH1A1KMT2AHTT | |
| SCHEMBL28380728 | 0.72 | ALDH1A1 (0.36) | TSHRALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL22995734 | 0.72 | TSHR (0.55) | TSHRTHRBALDH1A1KMT2ACHRM2 | |
| SCHEMBL295285 | 0.72 | TSHR (0.55) | TSHRTHRBALDH1A1KMT2ACHRM2 | |
| SCHEMBL4591972 | 0.72 | THRB (0.50) | TSHRTHRBALDH1A1CHRM2CHRM1 | |
| SCHEMBL1314414 | 0.71 | KIF11 (0.39) | ALDH1A1KMT2ACHRM3CYP2D6 | |
| Styrene SCHEMBL25312124 | 0.71 | TSHR (0.53) | TSHRTHRBALDH1A1KMT2A | |
| SCHEMBL238595 | 0.70 | THRB (0.51) | TSHRTHRBALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |