Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788358 | 0.85 | SMN1; SMN2 (0.38) | HRH3 | |
| SCHEMBL23788363 | 0.82 | USP1 (0.32) | — | |
| SCHEMBL12437113 | 0.82 | HRH3 (0.41) | HRH3 | |
| SCHEMBL26972254 | 0.80 | HRH3 (0.43) | HRH3 | |
| SCHEMBL12424502 | 0.80 | MEN1 (0.38) | HRH3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL799949 | 0.79 | THRA (0.38) | — | |
| SCHEMBL24827850 | 0.77 | OPRM1 (0.30) | — | |
| SCHEMBL26973851 | 0.77 | GNAO1 (0.36) | HRH3CHRM2CHRM1CHRM3 | |
| SCHEMBL6379437 | 0.76 | NCF1 (0.45) | HRH3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL18692703 | 0.76 | PDE7A (0.41) | HRH3CHRM2CHRM4CHRM1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275522-A1 | PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275522-A1 | PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | CDK2, CDK5, CDK6 | HRH3 3812/4885CHRM2 4613/4885CHRM4 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.