SCHEMBL2379010

SCHEMBL2379010

N#CN(C(=N)N)c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.47
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 3/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
KEAP1 Q14145 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30176884 1.00 SIGMAR1 (0.47) SIGMAR1CA1CA2KDM4EGAA
SCHEMBL2418864 0.77 ALDH1A1 (0.36) KDM4EGAAHTTCYP1A2ALDH1A1
SCHEMBL2431069 0.76 SIGMAR1 (0.55) SIGMAR1KDM4EGAAHPGDHTT
SCHEMBL7753428 0.73 SIGMAR1 (0.52) SIGMAR1KDM4EGAAHPGDHTT
SCHEMBL7401131 0.71 SIGMAR1 (0.53) SIGMAR1CA1CA2KDM4EGAA
SCHEMBL3068495 0.70 SIGMAR1 (0.49) SIGMAR1KDM4EGAAALDH1A1
SCHEMBL20263722 0.70 SIGMAR1 (0.51) SIGMAR1CA1CA2KDM4EGAA
SCHEMBL6831348 0.69 SIGMAR1 (0.47) SIGMAR1KDM4EGAAALDH1A1
SCHEMBL8854244 0.69 KMT2A (0.31) MAPT
SCHEMBL7411647 0.68 SIGMAR1 (0.49) SIGMAR1CA1CA2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380494-A1 COMPOSITION FOR ISOLATING TISSUE Solventum Intellectual Properties Company (US) 2024-06-12 EP disclosed
US-11827864-B2 Wipe with a guanidinyl-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-28 US disclosed
US-11766386-B2 Medical composition containing guanidinyl-containing polymer(s) and carrageenane(s) 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-26 US disclosed
WO-2023067453-A1 COMPOSITION AND PROCESS FOR TREATING A DISORDER IN THE ORAL CAVITY OF A MAMMAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-04-27 WO disclosed
US-20230100885-A1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-03-30 US disclosed
WO-2023012556-A1 COMPOSITION FOR ISOLATING TISSUE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-09 WO disclosed
US-11123267-B2 Dental retraction composition with guanidinyl-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-21 US disclosed
US-20210032578-A1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-02-04 US disclosed
EP-3013146-B1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER 3M INNOVATIVE PROPERTIES CO (US) 2020-11-25 EP disclosed
US-10844337-B2 Wipe with a guanidinyl-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-24 US disclosed
US-20170240591-A1 LIGAND FUNCTIONALIZED POLYMERS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2017-08-24 US disclosed
US-20170049926-A1 REMOVABLE FILM FORMING GEL COMPOSITIONS AND METHODS FOR THEIR APPLICATION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2017-02-23 US disclosed
EP-2889625-B1 LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2016-09-14 EP disclosed
US-20160115430-A1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2016-04-28 US disclosed
EP-2889625-A1 LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS 3M Innovative Properties Company (US) 2015-07-01 EP disclosed
EP-2542889-B1 LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2015-03-25 EP disclosed
US-20130224825-A1 LIGAND FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-29 US disclosed
US-20130217032-A1 LIGAND FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-22 US disclosed
US-8435776-B2 Ligand functionalized polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-05-07 US disclosed
US-20110217752-A1 LIGAND FUNCTIONALIZED POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844337-B2 Wipe with a guanidinyl-containing polymer GNPDA1, GDA, PGLS SIGMAR1 1725/4885CA1 4286/4885CA2 4456/4885
US-11766386-B2 Medical composition containing guanidinyl-containing polymer(s) and carrageenane(s) GANC, GMPS, MGAM SIGMAR1 1182/4885CA1 1562/4885CA2 590/4885
US-11123267-B2 Dental retraction composition with guanidinyl-containing polymer GMPS, PRMT9, PRMT5 SIGMAR1 2267/4885CA1 4310/4885CA2 4348/4885
US-20210032578-A1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER GNPDA1, GDA, PGLS SIGMAR1 1725/4885CA1 4286/4885CA2 4456/4885
US-11827864-B2 Wipe with a guanidinyl-containing polymer GNPDA1, GDA, PGLS SIGMAR1 1725/4885CA1 4286/4885CA2 4456/4885
US-20130224825-A1 LIGAND FUNCTIONALIZED POLYMERS SELPLG, CD69, SIGLEC7 SIGMAR1 127/4885CA1 1407/4885CA2 4646/4885
US-20110217752-A1 LIGAND FUNCTIONALIZED POLYMERS SELPLG, CD69, SIGLEC7 SIGMAR1 127/4885CA1 1407/4885CA2 4646/4885
US-20170240591-A1 LIGAND FUNCTIONALIZED POLYMERS SELPLG, CD69, SIGLEC7 SIGMAR1 127/4885CA1 1407/4885CA2 4646/4885
US-20230100885-A1 WIPE WITH A GUANIDINYL-CONTAINING POLYMER GNPDA1, GDA, PGLS SIGMAR1 1725/4885CA1 4286/4885CA2 4456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.