Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378581 | 0.81 | OPRM1 (0.53) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL2378578 | 0.80 | OPRM1 (0.51) | OPRM1OPRL1OPRK1 | |
| SCHEMBL2781209 | 0.80 | OPRM1 (0.57) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL2380060 | 0.78 | OPRL1 (0.55) | OPRM1OPRL1OPRK1 | |
| SCHEMBL17438590 | 0.78 | OPRM1 (0.52) | OPRM1OPRL1OPRK1 | |
| SCHEMBL303247 | 0.70 | OPRL1 (0.63) | OPRM1OPRL1OPRK1 | |
| SCHEMBL517752 | 0.70 | OPRL1 (0.69) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL2379087 | 0.69 | OPRL1 (0.62) | OPRM1OPRL1OPRK1 | |
| SCHEMBL2378995 | 0.69 | OPRM1 (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL15356038 | 0.69 | OPRM1 (0.46) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | OPRM1 3702/4885OPRL1 2478/4885OPRK1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.